For example, elevated serum and urine levels of Neutrophil Gelatinase-Associated Lipocalin (NGAL), a glycoprotein produced by epithelial tissues throughout the body, have been associated with AKI in the setting of sepsis (Ostermann et al. 2012; Bagshaw et al. 2010; Martensson et al. 2010). This evidence concerns the gene LCN2 and acute kidney injury.