THEMIS2 and ovarian carcinoma: Phenotype-genotype association analyses of allele positivity of the icb-1 gene SNPs revealed that A allele positivity of SNP rs1467465 was more frequent in patients with ovarian cancer than in the control group of healthy women (0.65 vs. 0.53, OR 1.632, 95% CI 1.072-2.483, p = 0.02) (Table 3).