Other up-regulated transcripts (Table S1) include chemokine ligand CXCL1, biglycan (BGN), and gelsolin (GSN), annexin-A2 (ANXA2), thymosin-β4 (TMSB4X) and member of Ras oncogene family (RAB10), whereas the transcripts down-regulated in pterygium were those of Serpin peptidase inhibitor, clade A member 1(SERPINA1) and chymase (CMA1). The gene discussed is SERPINA1; the disease is pterygium.