The top associated liver gene network altered by WD + AF but were not altered with WD when both conditions were compared to CTL included: ‘Gene Expression, Carbohydrate Metabolism, Molecular Transport’ (score: 29; up-regulated mRNAs: Ltb, Nr0b2, Cd36, Foxoa2, Hnf3; down-regulated mRNAs: Pepck, Pck1, Slc2a2, Ahr, Ivns1abp) (Figure 5). Here, PCK1 is linked to atrial fibrillation.