BAX and infectious otitis media: The deregulation of crypt cellular proliferation in the colon of the AOM-injected rats was associated with (Bcl-2/Bax >1), while the upregulation of Bax in A. ilicifolius treatment groups caused a change in the Bcl-2/Bax ratio value which was reserved to (Bcl-2/Bax <1) (Figure 8).