In line with this, Western blot analysis indicated that the expression level of Ki-67, a well-known marker for tumor cell proliferation, was lower in the group treated with cryoablated tumor extracts than in the control group (P < 0.05) (Figure 4(b)), indicating the inhibitory effect of cryoablated tumor extracts on tumor cell proliferation. Here, MKI67 is linked to neoplasm.