ITGAX and atherosclerosis: The transient depletion of DCs in mice carrying a transgene encoding a diphtheria toxin receptor under the control of the CD11c-promoter was shown to induce apoptosis in CD11c+ plaque-macrophages with subsequent proinflammatory effects on atherosclerosis [27], or prevailing effects of other cell subsets (Zernecke et al., unpublished observations).