After adjustment for age, BMI, BMD, a history of two or more falls, current smoking, current drinking, previous fractures, hypertension, diabetes, total cholesterol, myocardial infarction, stroke, adiponectin, osteocalcin, leptin, and 25(OH)D, it was noteworthy that BMD, age, a history of two or more falls, and adiponectin were associated with vertebral fractures. This evidence concerns the gene LEP and Stroke.