Most of the collagen type I (Figure 1C) and uromodulin fragments (Figure 1C) were in lower abundance in advanced CKD while beta-2-microglobulin, apolipoprotein AI and protein S100-A9 fragments were in higher abundance in advanced CKD (Figure 1C) in accordance with previous findings [7], [8]. The gene discussed is S100A9; the disease is chronic kidney disease.