PECAM1 and neoplasm: As shown in Fig 6a, CD31 staining was used to detect vessels in U87-EGFRvIII tumors and showed a significant decrease in the number of tumor vessels in mice treated with IP10-scFv/EGFRvIII peptide-pulsed, DC-induced CTLs or IP10-scFv compared to those in the control group (P < 0.01).