The autosomal dominant missense mutations c.632T>C (p.F211S) and c.589G>A (p.D197N) in the NIDO domain have been clearly associated with mid-frequency sensorineural hearing loss [16], suggesting a genotype-phenotype correlation between mutations in the NIDO domain of TECTA and mid-frequency sensorineural hearing loss. Here, TECTA is linked to hearing loss disorder.