HTT and Huntington disease: Post mortem cortex homogenates of HD patients (HD-1 (Q46/17), HD-2 (Q43/19), HD-3 (Q43/17), HD-4 (Q45/16)) and non-HD control donors (C-1, C-2, C-3) were tested and estimated amounts of HTT for each sample were calculated using standard curves of recombinant full length human mutant (Q46) HTT protein (Figure 6B).