IL17A and myeloid sarcoma: However, the strong inflammatory response overstimulated by IL-17 contributes to the pathogenesis of various human and animal diseases, such as rheumatoid arthritis, multiple sclerosis (MS), experimental autoimmune encephalomyelitis (EAE; a mouse model of MS) and allergen-induced pulmonary inflammation (Ye et al., 2001 ▶; Nakae et al., 2002 ▶; Iwakura & Ishigame, 2006 ▶; Schnyder-Candrian et al., 2006 ▶; Conti et al., 2009 ▶; Gonzalez-García et al., 2009 ▶; Hu et al., 2011 ▶).