TP53 and Diamond-Blackfan anemia: Upregulation of the transcription factor p53 is involved in DBA pathogenesis as p53 inhibition ameliorates hematopoietic and developmental defects in animal models of DBA (Danilova et al., 2011; Danilova et al., 2008; Dutt et al., 2011; McGowan et al., 2008).