TGFB1 and colonic neoplasm: In other work, TGFβ-induced Snail expression in hepatocytes was found to be dependent on p50/p65 binding at −162 bp [53], and p65 was able to activate Snail promoter in colon cancer cells via a region between −194 and −78 bp [54]; these studies indicate that the subunit specificity is likely cell type and stimulus dependent.