FOLR1 and cancer: More recently, significant differences (P<0.0001) were observed for median serum FOLR1 concentrations between 100 cancer-free women (median = 500 pg/ml) and 100 patients with ovarian carcinoma overall (median = 1,500 pg/ml), and separately for early-stage (median = 1,100 pg/ml) and late-stage (median = 2,200 pg/ml) ovarian carcinoma, using an enzyme-linked immunosorbent assay [30].