Severely immune-compromised women (CD4 <200 cells/mm3) were also found to be at a higher risk for the development of both SIL (aOR: 1.9; 95% CI: 1.1–5.9) and HSIL (aOR: 5.7; 95% CI: 1.1–7.2) compared to those with CD4 cell count above 200 cells/mm3. The gene discussed is CD4; the disease is squamous cell intraepithelial neoplasia.