Chromatin immuno-precipitation (ChIP) experiments using an anti-E2F1 antibody showed that infection with wild-type GFP-EBV significantly decreases the recruitment of E2F1 to ERE1 in RPMI and two independent LCLs (Figure 3B), while EBVΔLMP1 did not have any impact on this event in RPMI (Figure 3B). Here, E2F1 is linked to infection.