IL4 and neoplasm: The balance of expression of Th1/Th2/Th3-type cytokines such as IL-4, IL-10, and TGF-β1 in the cervical mucosa, cervical mucus [9], and tumor cells during HPV infection influences the immune status in the local cervical microenvironment and determines the persistence of HPV, progression of dysplasia into invasive cancer, and cervical cancer progression [4–6].