Previously, we reported that IL-10 and TGF-β1 are expressed in cervical lesions; therefore, the development of SIL and cervical cancer is preferentially associated with the expression of immunosuppressive cytokines (IL-10 and TGF-β1) and Th2-type cytokines (IL-4/IL-6) [26]. This evidence concerns the gene TGFB1 and squamous cell intraepithelial neoplasia.