FOXO1 and chronic myelogenous leukemia, BCR-ABL1 positive: CD34+ CML cells were treated with 150 nM dasatinib for 24 hours, at which time IF showed relocalization of total FOXO1 and 3a from cytoplasm (Fig. 2D, a–f) to nucleus (Fig. 2D, k–p), while little effect was seen with FOXO4.