However, compared with the Kd (56.64 nmol/L) and IC50(0.35–2.81 nmol/L) in the study of exendin-4 imaging we formly conducted, the affinity of liraglutide with GLP-1 receptors seems lower despite two different insulinoma cell lines(INS-1 and Rin-m5f). Here, GLP1R is linked to pancreatic insulinoma.