VEGFA and colonic neoplasm: Our results showed strong VEGF immunoreactivity in all colon tumors analyzed, independent of genotype (Fig. 4C, C′, D and D′), whereas VEGF was only weakly present in the normal colon epithelium of untreated mice (Fig. 4A, A′, B and ′) and near the tumors of injected mice (data not shown).