The inhibitory effects of WP1066 in the gp130757FF mouse model of gastric cancer, recapitulate and extend the outcomes of STAT3 haploinsufficiency generated genetically in the same mouse model [26], as well as the use of systemic antisense oligonucleotides against STAT3 [12], thus underscoring the importance of activated STAT3 signalling in facilitating gastric tumourigenesis. Here, STAT3 is linked to gastric cancer.