Other studies reported autoantibodies to HMG-17 in 10/29 (34%) SLE sera [122]and in 47% of pauciarticular onset JRA [126] and antibodies to HMG-1 and HMG-2 in 10% of SLE [122] and 39% of JRA patients [125]. Here, HMGB2 is linked to systemic lupus erythematosus.