CXCL8 and gastric cancer: IL-8 production has been observed in vitro in a wide variety of cells including monocytes, T lymphocytes, neutrophils, vascular endothelial cells, dermal fibroblasts, keratinocytes, hepatocytes, and human gastric cancer cells, while the production of CXCL2 and CXCL3 was only described in monocytes, fibroblasts, and endothelial cells [44, 45].