The results shown in Figure 1 also demonstrated that PBMNCs from T2DM patients secreted significantly (P < 0.05) higher amounts of IL-6 (256.7 ± 81.1) and TNF-alpha (96.1 ± 17.5) compared with the cells from ND controls (IL-6: 128.3 ± 32.3, TNF-alpha: 78.0 ± 13.6). This evidence concerns the gene IL6 and type 2 diabetes mellitus.