The function of FAM46C is unknown, although recent sequencing and homology studies have shown that its expression is correlated to both that of ribosomal proteins and eukaryotic initiation/elongation factors involved in protein translation [5]. FAM46C is considered a gene of significance as it has been shown to be frequently mutated in myeloma whilst also being independently correlated to a poor prognosis [5, 57, 58, 63]. Here, TENT5C is linked to plasma cell myeloma.