As shown in Figure 1, the frequencies of Th22 (CD4+ IFN-γ− IL-17− IL-22+), Th17 (CD4+ IFN-γ− IL-17+), and Th1 (CD4+ IFN-γ+) in total Th cells were all significantly higher in diabetic patients with CHD (n = 42) than those without CHD (n = 67). The gene discussed is CD4; the disease is coronary artery disorder.