BCL2L11 and acute lymphoblastic leukemia: Recent studies of the pro-apoptotic protein BIM, which is involved in the apoptosis of glucocorticoid-sensitive (CEM-C7) and -resistant (CEM-C1) acute lymphoblastic leukemia CEM cells, have shown that treatment with dexamethasone plus RU486 blocked apoptosis and BIM expression in CEM-C7 cells [65].