Here we sought to replicate and extend the previous findings by quantifying BDNF and trkB−TK+ mRNA expression by in situ hybridization in the DLPFC, OFC, ACC, STG and inferior temporal gyrus (ITG) of 60 subjects in the Stanley Neuropathology Consortium comprising 15 subjects in each of the four groups: schizophrenia, BPD, major depression (MDD) and unaffected controls. This evidence concerns the gene BDNF and schizophrenia.