A study by the Spanish Group for Sarcoma Research (GEIS) of 162 patients with GIST, treated between 1994 and 2001, found that in a multivariate analysis for RFS, the presence of high cellularity and deletions in codons 557–558 within KIT exon 11 were associated with recurrence [11]. The gene discussed is KIT; the disease is gastrointestinal stromal tumor.