PTX3 and neoplasm: These include: the damage receptor for advanced glycation end products (RAGE) and the purine receptor (P2X7R), the vascular epidermal growth factor A (VEGF) involved in tumor angiogenesis, the inducible enzymes ciclo-oxygenase-2 (COX2) responsible for prostaglandins synthesis, the acute phase protein pentraxin 3 (PTX3) and the C-X-C chemokine receptor 4 (CXCR4) of stromal cell-derived factor, regulator of invasive growth and metastasis formation.