RELA and Cerebral ischemia: Similarly, the protection of hypothermia and electrical acupuncture on brain damage was proved as well to be via modulating the activation of NF-κB/p65 [29], [30].Consistent with these reports, we not only demonstrated that transient ischemia induced activation of NF-κB/p65, but also found that ischemic postconditioning protects neuronal apoptosis caused by cerebral ischemia and reperfusion via inhibiting of NF-κB/p65 activation.