At step 1 of the Heckman two-step correction, we found that erythema significantly influences the increase in proinflammatory cytokines levels (IL-1β, IL-2, IL-6, and TNF-α), as stated by the corresponding P value in (1) (P = 0.00001); results are shown in Table 3. The gene discussed is IL2; the disease is Erythema.