PRNP and prion disease: In the review article “Identification of misfolded proteins in body fluids for the diagnosis of prion diseases” available at the following link: http://www.hindawi.com/journals/ijcb/2013/839329/, F. Properzi and M. Pocchiari give an up-to-date and comprehensive overview of the assays for detecting pathological forms of PrP in body fluids, highlighting the technological progress made in recent years.