Moreover, the levels of FSH and LH in Klinefelter’s syndrome, Chromosome polymorphism, and Robertsonian translocation groups, were significantly higher than those in the control group (FSH levels p=0.000), (p=0.000), and (p=0.087) respectively, LH levels (p=0.000), (p=0.002), and (p=0.007) respectively, whereas no significant difference was found in those levels between 47, XYY group and control group. This evidence concerns the gene BRD2 and Klinefelter syndrome.