Based on the relationship between high CAHM methylation and CRC revealed by the bisulphite-tag and bisulphite deep sequencing data, the HUGO Gene Nomenclature Committee (HGNC) approved renaming of LOC105526820 as Colon Adenocarcinoma HyperMethylated (non-protein coding), gene symbol CAHM. The gene discussed is CAHM; the disease is colorectal carcinoma.