Reovirus infection induced a significantly higher percentage of TUNEL positive cells in KRAS mutant HCT116 cells with 12.22 ±0.24% (mean ± SEM) apoptotic TUNEL positive cells compared to Hke3 cells 4.66 ± 0.345% (mean ±SEM) (Figure 3a and b). Here, KRAS is linked to Reoviridae infectious disease.