Likewise, chromosome band 16p13 contains, apart from CREBBP, also the CBFB gene which is fused to MYH11 in the subset of AML with inv(16)(p13q22) [34] as well as GLIS2 which is a partner in the fusion CBFA2T3-GLIS2 generated by inv(16)(p13q24) [35]. The gene discussed is CBFB; the disease is acute myeloid leukemia.