This approach was used to identify the WWTR1-CAMTA1 and YWHAE-FAM22A/B chimeric genes in epithelioid hemangioendothelioma and high-grade endometrial stromal sarcomas, respectively [21], [22], ZC3H7-BCOR in endometrial stromal sarcomas [23], IRF2BP2-CDX1 in a mesenchymal chondrosarcoma [24], and EWSR1-YY1 in a subset of mesotheliomas [25]. The gene discussed is YY1; the disease is endometrioid stromal sarcoma.