Clusterin participates in Aβ, PrP(res), and α-synuclein aggregation in Alzheimer’s disease, prionpathies, and α-synucleinopathies, respectively (Ferrer et al. 2005; Howlett et al. 2013; Sasaki et al. 2002). The gene discussed is CLU; the disease is synucleinopathy.