STIM1 and esophageal squamous cell carcinoma: In contrast to previously observed increases in STIM1 expression in cervical cancer [14], expression of STIM1 in ESCC tumor tissues did not differ statistically from that in normal esophageal epithelial tissues, and stim1 mRNA was found to be even reduced in ESCC tumor tissues (Fig. 1C and Supplementary Fig. S1A).