Similarly NAT of interleukin (IL) 1 beta) (Lu et al., 2013), iNOS (inducible nitric oxide synthase) (Yoshigai et al., 2013), and ubiquitin c-terminal hydrolase (uch) (Carrieri et al., 2012), Huntington's disease (Chung et al., 2011) suppress expression of their complementary transcripts. The gene discussed is NOS2; the disease is juvenile Huntington disease.