LTBI subjects, due to the increasing use of biological drugs, such as tumor necrosis factor-α (TNF-α)/Interleukin (IL)-12/IL-23 blockers for the treatment of inflammatory diseases like rheumatoid arthritis, Crohn’s disease, and psoriasis, have major risk to progress toward active disease more than other subjects (3, 7). Here, TNF is linked to psoriasis.