NFKB1 and primary effusion lymphoma: Our findings suggest that using different strategies of NFκB inhibition may be a valid therapeutic strategy in patients with uncontrolled viremia, such as in patients receiving immunosuppressive therapy; AIDS patients; and at risk patients who have an increased likelihood of developing HHV8 associated diseases including PEL and Multicentric Castleman’s disease, both of which have high levels of lytic viral replication.