CD8+ T cells are known to be involved in autoimmune disease such as multiple sclerosis (MS) (Babbe et al., 2000), but do not mediate the effects of 1,25D in suppressing the murine form of MS, experimental autoimmune encepholmyelitis (EAE) (Meehan and DeLuca, 2002). Here, CD8A is linked to myeloid sarcoma.