Initial studies to explore whether SLC4A7 plays a similar role for cell migration have been conducted using pharmacological inhibitors of Na+/H+ exchange (5-(N-ethyl-N-isopropyl) amiloride, EIPA) and Na+, HCO−3 cotransport (S0859) in Δ NErbB2-expressing MCF-7 breast cancer cells: EIPA was surprisingly shown to enhance cell migration while S0859 had no effect (Lauritzen et al., 2012). This evidence concerns the gene SLC4A7 and breast cancer.