Interestingly, only 10–20% of the investigated human breast carcinomas in our study showed upregulation or gene amplification of the ErbB2 receptor, suggesting that upregulated SLC4A7 expression is of general importance in breast cancer and not restricted to cancers characterized by increased ErbB2 signaling (Boedtkjer et al., 2013). Here, ERBB2 is linked to breast cancer.