SLC26A3 downregulation correlates with colon tumor progression (Antalis et al., 1998); and in congruence with this, expression levels for SLC26A3 have been reported to be controlled by miR-31, which is upregulated in tumors from patients with progressive CRC compared to patients with disease control (Mosakhani et al., 2012). Here, SLC26A3 is linked to colorectal carcinoma.