A10 aptamer (Apt), which recognizes the extracellular domain of the prostate-specific membrane antigen (PSMA), was conjugated to unimolecular DOX loaded micelles consisting of a H40 dendritic core, an inner shell of hydrophobic PLA and an outer hydrophilic PEG shell (H40-PLA-PEG-Apt) for targeted prostate cancer therapy(Xu et al., 2013b). This evidence concerns the gene FOLH1 and prostate carcinoma.