VLDLR and cerebellar ataxia: With regard to VLDLR gene mutation in some cerebellar ataxias, Moheb et al. (2008) argued that “VLDLR deficiency alone is sufficient to cause the human DES phenotype.” Although a similar mutation in the same gene was also found in some families with UTS Type-I (Caglayan, 2008), this was not the rule either for DES or UTS cases.