However, LPS effect was stronger in WT mice (fold changes for vGlut: −2.71, p < 0.001; PSD95: −2.05, p < 0.001) than in 3xTg-AD mice (fold changes for vGlut: −1.22, p < 0.05; PSD95: −1.26, p < 0.05). The gene discussed is DLG4; the disease is Alzheimer disease.