Sholl analysis revealed an overall effect of genotype [Multivariate Test: F(21, 168) = 2.53; p < 0.001] but no significant effect of LPS treatment [Multivariate Test: F(21, 168) = 0.79; p > 0.05] suggesting a different branching pattern between Dcx-positive neurons of WT and 3xTg-AD mice. This evidence concerns the gene DCX and Alzheimer disease.