On this layer, LPS injection also induced a decrease in the number of vGlut [F(1, 16) = 66.63, p < 0.001; −1.56-fold] and PSD95-positive puncta [F(1, 16) = 12.53, p < 0.01; −1.31-fold] of Dcx cells from WT mice but no effect was detected in 3xTg-AD mice. This evidence concerns the gene DLG4 and Alzheimer disease.