With respect to this, the polymorphisms ABO (histoblood group ABO system transferase) rs579459, PPAP2B (phosphatidic acid phosphatase type 2B) rs17114036, and ADAMTS7 (metallopeptidase with thrombospondin type 1 motif, 7) rs3825807 have been identified as significant genetic variants associated with CAD in nonrheumatic Caucasian individuals [14]. This evidence concerns the gene PLPP3 and coronary artery disorder.