Previous studies have described the ABO rs579459, PPAP2B rs17114036, and ADAMTS7 rs3825807 polymorphisms as genetic variants associated with coronary artery disease [14] and the PIK3CG rs17398575 and EDNRA rs1878406 polymorphisms as the most significant signals related to the presence of carotid plaque [15] in nonrheumatic Caucasian individuals. This evidence concerns the gene EDNRA and coronary artery disorder.